![]() officinale is veno-occlusive disease, a non-thrombotic obliteration of small hepatic veins leading to cirrhosis and eventually liver failure (3). The main type of liver damage caused by S. Sometimes there is also damage to the lungs. They can produce veno-occlusive disease of the liver with clinical features like abdominal pain with ascites, hepatomegaly, splenomegaly, anorexia, nausea, vomiting, and diarrhea. Certain representatives of this class and the plants in which they occur are hepatotoxic, as well as mutagenic and carcinogenic. Symphytum officinale contains pyrrolizidine alkaloids, which are the subject of a separate monograph. Herbal medicines that provide more than 1 mg internally or more than 100 mg externally per day, when used as directed, are not permitted herbal medicines that provide 0.1-1 mg internally or 10-100 mg externally per day, when used as directed, may be applied only for a maximum of 6 weeks per year, and they should not be used during pregnancy or lactation. The German Federal Health Office has restricted the availability of botanical medicines containing unsaturated pyrrolizidine alkaloids (1,2). We recommend considering weekend/holiday delays when ordering (I.E.Symphytum officinale (black wort, boneset, bruise wort, comfrey, knitback, knitbone, slippery root) contains pyr-rolizidine alkaloids, such as lasiocarpine and symphytine, and their N-oxides, and has repeatedly been associated with hepatotoxicity.Ĭomfrey products have been withdrawn from the market in several countries, including the USA and the UK. Although the product may not be cold when it arrives, this ice pack helps maintain a cooler temperature during transit. They are also shipped with a FREE ice pack. Probiotics are refrigerated in our warehouse to ensure quality and optimal potency. While in these cases, ingredients are usually the same and only the packaging has been updated, we always recommend that you read labels, warnings and directions of all products before use and not rely solely on the information provided by Healthy Planet Canada. Some items may occasionally ship with alternate packaging (recently updated by the supplier or manufacturer). However, some manufacturing changes to packaging or ingredients may be pending updates on our website. Healthy Planet Canada wants to ensure the complete and total accuracy of the product images and information contained on our website. Pharmacy Practice+ and Profession Santé 2017 Survey on OTC Counselling and Recommendations. They are generally recommended by health care practitioners and information relevant to one’s symptoms can be researched with specialized books or articles.Įach tube contains 4 g (approximately 80 pellets).īoiron is the #1 brand of homeopathic medicines recommended by pharmacists. These medicines may be used in the framework of individualized treatment that might involve different pathologies and are based on the patient’s specific symptoms. In Canada, they are available in varying dilutions and have no mention of a therapeutic indication. ![]()
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